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Masteron Propionate

(5 customer reviews)

$110.00

Masteron is the trade name for the anabolic steroid Drostanolone. Materon is an injectable oil-based anabolic steroid, and is derived from Dihydrotestosterone (DHT), which makes Masteron a member of the DHT-derived family of anabolic steroid derivatives and analogues.

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Masteron is the trade name for the anabolic steroid Drostanolone. Materon is an injectable oil-based anabolic steroid and is derived from Dihydrotestosterone (DHT), which makes Masteron a member of the DHT-derived family of anabolic steroid derivatives and analogues. Essentially, all anabolic steroid analogues and derivatives are all modifications in one way or another of the three primary anabolic steroids naturally found in all humans: Testosterone, Dihydrotestosterone, and Nandrolone. In this case, Masteron’s progenitor (or parent) hormone is Dihydrotestosterone. Other anabolic steroids that belong in this family of DHT derivatives include Anavar, Winstrol, Anadrol, Primobolan, and various others. Masteron is not regarded as a very strong anabolic steroid but neither is it a weak one. Its anabolic strength is generally regarded as moderate at best (anabolic rating of 62 – 130), while its androgenic strength is fairly low (25 – 40). This demonstrates a stark difference when compared to Testosterone, which is the number one natural and original anabolic steroid and is used as the reference measuring bar by which all other anabolic steroids are compared to and measured against. Testosterone in comparison holds an anabolic and androgenic strength rating of 100 for both respectively.

Masteron’s details (as Drostanolone) were first released and published in 1959. The origins of this compound are quite interesting, as Syntex had synthesized and developed this anabolic steroid. Syntex was also known for the development of other popular anabolic steroids as well, such as Anadrol and Methyldrostanolone (AKA Superdrol). It would not be until about 10 years later after the publishing of its details that Masteron would finally be released onto the market. Lilly and Syntex had worked together in the development and marketing of different pharmaceuticals, and both companies had an agreement that both entities would share research and development (R&D) resources and costs with the trade-off that one of the companies would obtain the rights to the drug. It was Lilly that ended up marketing Masteron under the brand name known as Drolban on the American market. Syntex also marketed this anabolic steroid, only they would look after its marketing and distribution on the international market instead.

Masteron was approved by the FDA at first as an antineoplastic agent in the treatment of female breast cancer patients. Masteron in particular fits very well into this role, as its lower and weaker androgenic strength rating in comparison to Testosterone could prove to be very beneficial in female users, as the incidence of virilization symptoms would be less prominent with Masteron than many other anabolic steroids which are known to possess strong androgenic strength ratings. Even the prescription information and guidelines expounded on this fact, stating that there is far less of a probability of developing virilization with Masteron in comparison to equal Testosterone Propionate doses. However, the problem here was that the initial prescription guideline for females was that of 300mg weekly of Masteron, which evidently proved to be too high of a dose for females as evidenced by the fact that virilization did occur in many patients at that dose. Virilization had also become an issue in female patients that had been administered Masteron in the long term.

Masteron’s popularity with bodybuilders and athletes did not begin until the 1970s and increased into the 1980s. As more effective breast cancer treatments were discovered and developed, Masteron began to lose its value in the medical field, and many different pharmaceutical manufacturers began to slowly discontinue the sale and production of this compound during this time. Drolban itself was officially pulled from the American market in the late 1980s, and two other branded Masteron preparations were soon after pulled from the market as well. Masteron today still remains on the list of approved medications, but it is not currently being manufactured, and therefore not being sold on American (or any Western) markets.

The specific name for Masteron is actually Dromostanolone (Drostanolone was a slightly more abbreviated name given to the compound shortly after its release). As mentioned previously, it is a modified derivative of DHT (Dihydrotestosterone), placing it into the family of DHT derivatives and analogs. Masteron is a modified form of DHT, where a methyl group is at the 2nd carbon (known as carbon alpha) atom. This modification is what is known to be responsible for the slight anabolic strength increase in comparison to Testosterone. This methyl group addition increases the anabolic strength by way of granting Masteron an increased resistance to being metabolized into inactive metabolites by the enzyme 3-hydroxysteroid dehydrogenase. This enzyme is present in large quantities in muscle tissue and is the enzyme that serves to metabolize any DHT that enters muscle tissue into two inactive metabolites:  3-Alpha Androstanediol and 3-Beta Androstanediol that are non-anabolic what so ever in muscle tissue. This is therefore the reason why DHT is not anabolic in muscle tissue at all, and many chemists and biologists believe that if the enzyme 3-hydroxysteroid dehydrogenase did not exist in muscle tissue, DHT would actually be a very potent and powerful anabolic steroid.

In any case, Masteron’s methyl group addition to alpha carbon 2 effectively eliminates its ability to be metabolized by this enzyme.

There exist two different variants of Masteron: Drostanolone Propionate, and Drostanolone Enanthate. The most popular variant is the Propionate variant, followed in popularity by the Enanthate variant. The explanation here will use Drostanolone Propionate as an example. Specifically, ‘Propionate’ is Propanoic acid, but once bound to Masteron it is properly referred to in chemistry as an ester bond (or ester linkage). Propanoic acid is bonded to the 17-beta hydroxyl group on the Drostanolone (Masteron) chemical structure. The addition of this ester modifies the hormone’s half-life and release rate, providing a much longer extended-release and half-life than if the hormone was not esterified. The primary reason for the augmentation of its half-life and release rate is that once Drostanolone Propionate enters the bloodstream, enzymes in the body will break the bond between the ester and the hormone, which takes varying amounts of time (the time taken for the bonds to be broken is dependent on the size of the ester – the longer and larger it is, the longer it will take). The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Masteron (or any anabolic steroid that was previously esterified) that is now free to do its work in the body. This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates and extended half-lives.

As a result, Drostanolone Propionate possesses a half-life of 2.5 days, and Drostanolone Enanthate possesses a half-life of 10 days. Esterification does nothing to modify the effects and characteristics of the hormone aside from augmenting the hormone’s release rates and half-lives.

Because Masteron is a DHT-derivative, it retains some of the same characteristics as its parent hormone, one of which is its inability to interact with the aromatase enzyme. The aromatase enzyme is the enzyme responsible for the conversion of androgens into Estrogen, of which Masteron is invulnerable to this process. Therefore, Masteron will exhibit no Estrogenic side effects at any dose, making Masteron completely void of the following risks: water retention and bloating, elevated blood pressure (as a result of water retention), possible fat gain/retention, and gynecomastia. Individuals using Masteron will only experience lean mass gains without the addition of water weight, which would otherwise serve to create a very puffy, soft, and bloated-looking physique. It is therefore an anabolic steroid preferred by the majority of bodybuilders and athletes as a ‘cutting’ compound considered very useful for pre-contest cycles and fat loss and cutting phases.

Due to its low to moderate anabolic strength, Masteron is not regarded as being a very good mass addition or bulking compound, and in fact, many experienced anabolic steroid users suggest that due to its higher price and its moderate anabolic strength, it is only of real value to competitive bodybuilders who wish to achieve a very hardened and ‘chiseled’ look to the physique once on-stage in a show. When stacked with other particular compounds, Masteron has been shown to bring out a ‘ripped’ physique to an even greater deal. However, these ‘hardening’ properties of Masteron do not exhibit themselves in the user unless he or she possesses a low enough body fat percentage to be able to allow these hardening effects to become visible. This leads to the next major property of Masteron.

Masteron has been demonstrated as being a moderate aromatase inhibitor, as well as possibly acting to block Estrogen at receptor sites on breast tissue. This is the reason for Masteron’s original and primary use as an advanced breast cancer treatment drug. This is also the reason why Masteron has been explained by many experienced users as having a ‘hardening’ and ‘chiseling’ effect on the physique when the body is very lean (under 10% body fat). Masteron works to inhibit the aromatase enzyme, thereby eliminating the ability for estrogen to be formed from aromatizable anabolic steroids through the process of aromatization. Essentially, this effectively reduces any water retention as Estrogen levels continue to decline from increasing numbers of disabled aromatase enzymes.

The specific name for Masteron is actually Dromostanolone (Drostanolone was a slightly more abbreviated name given to the compound shortly after its release). As mentioned previously, it is a modified derivative of DHT (Dihydrotestosterone), placing it into the family of DHT derivatives and analogues. Masteron is a modified form of DHT, where a methyl group at the 2nd carbon (known as carbon alpha) atom. This modification is what is known to be responsible for the slight anabolic strength increase in comparison to Testosterone. This methyl group addition increases the anabolic strength by way of granting Masteron an increased resistance to being metabolized into inactive metabolites by the enzyme 3-hydroxysteroid dehydrogenase. This enzyme is present in large quantities in muscle tissue and is the enzyme that serves to metabolize any DHT that enters muscle tissue into two inactive metabolites:  3-Alpha Androstanediol and 3-Beta Androstanediol that are non-anabolic what so ever in muscle tissue. This is therefore the reason why DHT is not anabolic in muscle tissue at all, and many chemists and biologists believe that if the enzyme 3-hydroxysteroid dehydrogenase did not exist in muscle tissue, DHT would actually be a very potent and powerful anabolic steroid.

In any case, Masteron’s methyl group addition to alpha carbon 2 effectively eliminates its ability to be metabolized by this enzyme.

There exist two different variants of Masteron: Drostanolone Propionate, and Drostanolone Enanthate. The most popular variant is the Propionate variant, followed in popularity by the Enanthate variant. The explanation here will use Drostanolone Propionate as an example. Specifically, ‘Propionate’ is Propanoic acid, but once bound to Masteron it is properly referred to in chemistry as an ester bond (or ester linkage). Propanoic acid is bonded to the 17-beta hydroxyl group on the Drostanolone (Masteron) chemical structure. The addition of this ester modifies the hormone’s half-life and release rate, providing a much longer extended-release and half-life than if the hormone was not esterified. The primary reason for the augmentation of its half-life and release rate is that once Drostanolone Propionate enters the bloodstream, enzymes in the body will break the bond between the ester and the hormone, which takes varying amounts of time (the time taken for the bonds to be broken is dependent on the size of the ester – the longer and larger it is, the longer it will take). The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Masteron (or any anabolic steroid that was previously esterified) that is now free to do its work in the body. This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates and extended half-lives.

As a result, Drostanolone Propionate possesses a half-life of 2.5 days, and Drostanolone Enanthate possesses a half-life of 10 days. Esterification does nothing to modify the effects and characteristics of the hormone aside from augmenting the hormone’s release rates and half-lives.

Because Masteron is a DHT-derivative, it retains some of the same characteristics as its parent hormone, one of which is its inability to interact with the aromatase enzyme. The aromatase enzyme is the enzyme responsible for the conversion of androgens into Estrogen, of which Masteron is invulnerable to this process. Therefore, Masteron will exhibit no Estrogenic side effects at any dose, making Masteron completely void of the following risks: water retention and bloating, elevated blood pressure (as a result of water retention), possible fat gain/retention, and gynecomastia. Individuals using Masteron will only experience lean mass gains without the addition of water weight, which would otherwise serve to create a very puffy, soft, and bloated-looking physique. It is therefore an anabolic steroid preferred by the majority of bodybuilders and athletes as a ‘cutting’ compound considered very useful for pre-contest cycles and fat loss and cutting phases.

Due to its low to moderate anabolic strength, Masteron is not regarded as being a very good mass addition or bulking compound, and in fact, many experienced anabolic steroid users suggest that due to its higher price and its moderate anabolic strength, it is only of real value to competitive bodybuilders who wish to achieve a very hardened and ‘chiseled’ look to the physique once on-stage in a show. When stacked with other particular compounds, Masteron has been shown to bring out a ‘ripped’ physique to an even greater deal. However, these ‘hardening’ properties of Masteron do not exhibit themselves in the user unless he or she possesses a low enough body fat percentage to be able to allow these hardening effects to become visible. This leads to the next major property of Masteron.

Masteron has been demonstrated as being a moderate aromatase inhibitor, as well as possibly acting to block Estrogen at receptor sites on breast tissue. This is the reason for Masteron’s original and primary use as an advanced breast cancer treatment drug. This is also the reason why Masteron has been explained by many experienced users as having a ‘hardening’ and ‘chiseling’ effect on the physique when the body is very lean (under 10% body fat). Masteron works to inhibit the aromatase enzyme, thereby eliminating the ability for estrogen to be formed from aromatizable anabolic steroids through the process of aromatization. Essentially, this effectively reduces any water retention as Estrogen levels continue to decline from increasing numbers of disabled aromatase enzymes.

Masteron is regarded by the bodybuilding community as being one of the ‘mild’ anabolic steroids when it comes to side effects. This is due in large part to the fact that Masteron is a DHT derivative. Having been derived from DHT, it, therefore, possesses all of the same (or similar) attributes and features that DHT does. This includes the inability to interact with the aromatase enzyme, and therefore be completely void of any Estrogen-related side effects.

As previously mentioned, Masteron is totally void of any estrogenic side effects by virtue of the fact that it is a DHT derivative. Not only does it completely avoid aromatization (conversion into Estrogen), evidence suggests that it behaves as a mild aromatase inhibitor as well. Side effects resulting from Estrogen buildup (such as water retention, bloating, fat retention and gain, and the development of gynecomastia) are completely avoided or reduced with the use of Masteron.

Though Masteron holds a weaker androgenic strength rating than Testosterone itself, androgenic side effects are still indeed possible with this compound, especially among those who may be particularly sensitive. Masteron side effects that include androgenic side effects include an increase in oily skin (as a result of increased sebum production/secretion), increased facial hair and bodily hair growth, as well as the increased risk of triggering MPB (Male Pattern Baldness) in those that are genetically sensitive or predisposed to it. Virilization (the development of male characteristics in women) is also a risk with female use, though its use in female breast cancer patients should attest to its acceptable nature as a female-use compound.

Masteron side effects in particular include greater negative impacts on cholesterol and the cardiovascular system than some other compounds. This is largely due to Masteron’s anti-estrogenic capabilities in the body. Its ability to reduce serum levels of Estrogen results in measurable reductions in HDL (‘good’) cholesterol, and increases LDL (‘bad’) cholesterol[4].

Masteron exhibits no hepatotoxicity (liver toxicity), but like any anabolic steroid, it does contribute to suppression/shutdown of the HPTA, thereby reducing endogenous production of Testosterone.

5 reviews for Masteron Propionate

  1. Kris (verified owner)

    I am highly satisfied with Masteron Propionate. It has provided me with awesome results. The price is fair and the quality is high grade. The packaging was good and the package arrived discreetly. The customer service was excellent and the support was fast.

  2. Blake (verified owner)

    I had a great experience with Masteron Propionate. It delivered excellent results and the price was fair. The quality of the product is high grade. The packaging was good and the package arrived discreetly. The customer service was excellent and the support was fast.

  3. Arthur (verified owner)

    Masteron Propionate is a top-notch product. The results I’ve achieved are awesome. The price is fair and the quality is high grade. The packaging was good and the package arrived discreetly. The customer service was excellent and the support was fast.

  4. Hammod (verified owner)

    I’m really impressed with the quality of Masteron Propionate. It has delivered amazing results for me. The price was fair and the packaging was good. The customer service was excellent and the support was fast. Highly recommended!

  5. Max (verified owner)

    I ordered Masteron Propionate and it was delivered to me very fast. The results are awesome and the price is fair. The quality of the product is high grade. The packaging was good and the package was discreet. The customer service was excellent and the support was fast.

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